Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0456206
PubChem CID
Molecular Formula
C68H102N26O19S4
Molecular Weight
1715.995 g/mol
Synonyms/Alias
N/A (Not available)
InChI Key
IYPRSLKNNQSHRB-SNIZTLIQSA-N
InChI
InChI=1S/C68H102N26O19S4/c1-32(2)16-40-58(104)90-45(53(70)99)25-114-116-28-48-63(109)89-44(24-95)60(...
IUPAC Name
3-[(1R,6R,9S,12S,15S,21S,24S,27S,30S,33R,36S,39S,45S,48S,53R)-53-[(2-aminoacetyl)amino]-24-(3-carbamimidamidopropyl)-6-carbamoyl-48-(hydroxymethyl)-30,36,45-tris(1H-imidazol-5-ylmethyl)-12,27-dimethyl-9-(2-methylpropyl)-8,11,14,20,23,26,29,32,35,38,44,47,50,52-tetradecaoxo-3,4,55,56-tetrathia-7,10,13,19,22,25,28,31,34,37,43,46,49,51-tetradecazatetracyclo[31.17.7.015,19.039,43]heptapentacontan-21-yl]propanoic acid
CAS Number
N/A (Not available)

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

117123 0 0 0 0 0 0 0 0999 V2000
-7.7817 -13.2232 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-7.3783 -11.7784 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-8.4278 -10...

Experimental Data

Activity Data

Target Ion Channel
Neuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-2/beta-3
Uniprot Accession Number
Function
Inhibitor
Species
Rattus norvegicus (Rat)
IC50
IC50: 44 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
not mention
Holding Potential
not mention mV
Temperature
not mention
Test Method
Patch-clamping
Test Species
Xenopus laevis oocyte

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
117
Rotatable Bonds
19
logP
-8.3915
Complexity
423.4344
TPSA (Ų)
693.5
H-Bond Donors
23
H-Bond Acceptors
27
Ring Count
7
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